GALEPZY PLUS (Tablet)

GALEPZY PLUS is a high-potency tablet formulation containing Gabapentin 100 mg + Methylcobalamin 500 mcg.

Composition: Gabapentin 100 mg + Methylcobalamin 500 mcg
Dosage Form: Tablet

Clinical Pharmacology

Gabapentin modulates neuronal excitability through interaction with the α2δ subunit of voltage-gated calcium channels and is used in the management of neuropathic pain. Methylcobalamin provides neurotropic vitamin B12 support.

Indications & Usage

May be used in the management of:

• Peripheral neuropathic pain
• Diabetic peripheral neuropathy
• Post-herpetic neuralgia
• Neuropathic pain associated with nerve injury
• Other clinically diagnosed neuropathic pain conditions
• Neurotropic nutritional support where vitamin B12 supplementation is appropriate

Contraindications

Known hypersensitivity to gabapentin or any component.

Warnings & Precautions

May cause dizziness and somnolence. Dose adjustment is required in renal impairment. Avoid abrupt discontinuation.

Drug Interactions

CNS depressant effects may be enhanced with opioids, sedatives and alcohol. Antacids may reduce gabapentin absorption.

Pregnancy & Lactation

Use during pregnancy only when clinically justified. Medical advice is required during breastfeeding.

Dosage & Administration

Dosage should be individualized according to indication, response and renal function.

Adverse Reactions

Dizziness, somnolence, fatigue, headache, peripheral edema, nausea and blurred vision.

Therapeutic Focus: Diabetic Neuropathy | Primary Specialty: Diabetology