MEFTAZEN is a high-potency tablet formulation containing Methylcobalamin 1500 mcg + Alpha Lipoic Acid 100 mg + Vitamin D3 1000 IU + Pyridoxine HCl 3 mg + Folic Acid 1.5 mg.
Film-Coated Tablet
Composition
Each film-coated tablet contains:
| Ingredient |
Strength |
| Alpha-Lipoic Acid |
100 mg |
| Pyridoxine Hydrochloride |
3 mg |
| Methylcobalamin |
1500 mcg |
| Folic Acid |
1.5 mg |
| Vitamin D3 |
1000 IU |
| Excipients |
q.s. |
Therapeutic Category
Antioxidant & Neurotropic Nutritional Supplement
Product Overview
MEFTAZEN combines alpha-lipoic acid, methylcobalamin, pyridoxine, folic acid and vitamin D3 to provide antioxidant and neurotropic nutritional support.
Clinical Pharmacology
Alpha-Lipoic Acid
Alpha-lipoic acid is an endogenous antioxidant involved in mitochondrial energy metabolism. It also participates in the regeneration of other antioxidants and has been investigated for its role in peripheral neuropathic conditions.
Methylcobalamin
Methylcobalamin is an active form of vitamin B12 involved in neuronal metabolism and myelin-related processes.
Pyridoxine
Vitamin B6 participates in amino-acid metabolism, neurotransmitter synthesis and normal neurological function.
Folic Acid
Folic acid is required for nucleotide synthesis, DNA replication and normal cellular division.
Vitamin D3
Vitamin D3 contributes to calcium metabolism and normal neuromuscular function.
Indications & Usage
MEFTAZEN may be used as an adjunctive nutritional formulation in:
- Peripheral neuropathic conditions
- Diabetic neuropathic symptoms
- Nutritional deficiencies involving B vitamins
- Conditions requiring antioxidant nutritional support
- Patients requiring neurotropic vitamin supplementation
Contraindications
Known hypersensitivity to any component of the formulation.
Warnings & Precautions
Patients receiving antidiabetic therapy should be monitored appropriately because alpha-lipoic acid may influence glucose metabolism.
Prolonged excessive intake of vitamin B6 should be avoided because chronic high exposure may itself cause peripheral sensory neuropathy.
Patients taking multiple vitamin preparations should avoid unnecessary duplication.
Drug Interactions
Potential interactions should be considered with:
- Antidiabetic medications
- Mineral-containing preparations
- Other vitamin-containing products
Patients should inform their physician of all prescription medicines, OTC medicines and supplements being taken.
Pregnancy & Lactation
Use during pregnancy and lactation should be based on professional medical advice.
Dosage & Administration
One tablet once daily or as directed by the physician.
Preferably administer with or after food unless otherwise advised.
Adverse Reactions
Possible adverse reactions include:
- Nausea
- Vomiting
- Abdominal discomfort
- Headache
- Skin reactions
- Symptoms of low blood glucose in susceptible individuals
Therapeutic Focus: Diabetic Neuropathy | Primary Specialty: Diabetology
