VYRACTAM (Injection)
VYRACTAM is a high-potency injection formulation containing Sulbactam 1 gm.
Composition: Sulbactam 1 g
Dosage Form: Injection
Clinical Pharmacology
Sulbactam is an irreversible beta-lactamase inhibitor. Its principal clinical role is in combination with susceptible beta-lactam antibacterial agents to inhibit beta-lactamase-mediated resistance.
Indications & Usage
Sulbactam should generally be used in combination with an appropriate beta-lactam antibiotic, according to the approved product and susceptibility profile, for management of susceptible bacterial infections.
Potential clinical settings may include:
- Serious hospital-acquired bacterial infections
- Respiratory tract infections
- Intra-abdominal infections
- Urinary tract infections
- Skin and soft-tissue infections
- Gynecological infections
- Surgical infections
Contraindications
Severe hypersensitivity to sulbactam or beta-lactam antibiotics.
Warnings & Precautions
Use should be guided by microbiological susceptibility and antimicrobial stewardship principles.
Drug Interactions
Interactions depend largely on the accompanying beta-lactam antibiotic and patient therapy.
Pregnancy & Lactation
Use when clinically indicated.
Dosage & Administration
Sulbactam dosing must be determined as part of an approved beta-lactam/beta-lactamase-inhibitor regimen. It should not be positioned on the website as a stand-alone antibacterial treatment.
Adverse Reactions
Injection-site reactions, diarrhea, nausea, rash and hypersensitivity reactions.
Therapeutic Focus: Antibiotic Injectable | Primary Specialty: General Medicine
