VYRACTAM (Injection)

VYRACTAM is a high-potency injection formulation containing Sulbactam 1 gm.

Composition: Sulbactam 1 g
Dosage Form: Injection

Clinical Pharmacology

Sulbactam is an irreversible beta-lactamase inhibitor. Its principal clinical role is in combination with susceptible beta-lactam antibacterial agents to inhibit beta-lactamase-mediated resistance.

Indications & Usage

Sulbactam should generally be used in combination with an appropriate beta-lactam antibiotic, according to the approved product and susceptibility profile, for management of susceptible bacterial infections.

Potential clinical settings may include:

• Serious hospital-acquired bacterial infections
• Respiratory tract infections
• Intra-abdominal infections
• Urinary tract infections
• Skin and soft-tissue infections
• Gynecological infections
• Surgical infections

Contraindications

Severe hypersensitivity to sulbactam or beta-lactam antibiotics.

Warnings & Precautions

Use should be guided by microbiological susceptibility and antimicrobial stewardship principles.

Drug Interactions

Interactions depend largely on the accompanying beta-lactam antibiotic and patient therapy.

Pregnancy & Lactation

Use when clinically indicated.

Dosage & Administration

Sulbactam dosing must be determined as part of an approved beta-lactam/beta-lactamase-inhibitor regimen. It should not be positioned on the website as a stand-alone antibacterial treatment.

Adverse Reactions

Injection-site reactions, diarrhea, nausea, rash and hypersensitivity reactions.

Therapeutic Focus: Antibiotic Injectable | Primary Specialty: General Medicine